National Geographic
August 25, 2005

Researchers have dramatically increased the life spans of mice by genetically engineering them to overproduce a protein called klotho. Not surprisingly, the discovery has spurred speculation that klotho could help humans live longer. The gene regulates production of klotho protein, which the team says works like an anti-aging hormone.
This relates to humans because, we have a klotho gene that is almost identical to the one that is in mice. Some studies have shown that natural alterations of the gene in both humans and mice can cause increased aging-related problems. These problems can be muscular atrophy or hardening of the arteries, but has not been linked to cancer or Alzheimer's disease, which is a good thing.
The study team do not know for sure if the klotho gene could benefit for humans as well as it does for mice. But they say that klotho is likely an important key to how humans age, but not a single regulator.

Armani Polynice
February 27, 2009